1566P - Down-regulation of target gene expression in human white blood cells (hWBCs) by MRX34, a liposomal miR-34 mimic: Next generation sequencing (NGS) results from a first-in-human trial of microRNA cancer therapy

K Kelnar,H.J Peltier,A.G Bader

doi:10.1093/annonc/mdw392.47

1566P - Down-regulation of target gene expression in human white blood cells (hWBCs) by MRX34, a liposomal miR-34 mimic: Next generation sequencing (NGS) results from a first-in-human trial of microRNA cancer therapy

K Kelnar, H.J Peltier + Show 1 more

Open Access

https://doi.org/10.1093/annonc/mdw392.47

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Journal: Annals of oncology : official journal of the European Society for Medical Oncology	Publication Date: Oct 1, 2016
Citations: 1	License type: elsevier-specific: oa user license

#Human White Blood Cells #Distinct Cellular Pathways + Show 8 more

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Abstract

e14078Background: Each microRNA (miRNA) modulates the expression of hundreds of genes across distinct cellular pathways, giving miRNA-based therapy the potential to simultaneously repress multiple ...

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