Abstract
ABSTRACT Background Quality of life in cancer patients is significantly reduced by anaemia and associated fatigue. Fatigue is one of the most common symptoms of cancer and cancer therapy. The aim of the present study was to evaluate fatigue in treatment-naive patients with solid tumours and after four months of cancer therapy using the Functional Assessment of Cancer Therapy-Fatigue (FACT-F) questionnaire. Methods Multicenter, prospective and observational study that included newly diagnosed cancer patients. Patients completed the FACT-F questionnaire at baseline and after four months of cancer therapy. Anaemia status (haemoglobin Results The study included 295 patients (153 females), mean age was 61.6 (±12.5). FACT-F score decreased by a mean of 2.4 points over the four months of cancer therapy (p Conclusions Severe fatigue is highly correlated with anaemia before and after cancer therapy. The prevalence of fatigue increased with cancer therapy. Treatment of both cancer-related and treatment-related anaemia could reverse fatigue and have a positive effect on quality of life of cancer patients. Disclosure All authors have declared no conflicts of interest.
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