Abstract
Hyperthermia is an important means of cancer treatment which is called “tumor green therapy”. The clinical heat therapy heating sources include ultrasound, microwave, alternating magnetic field, infrared laser. However, it is still difficult to accurately measure the temperature of tumor hyperthermia and the dose of hyperthermia. Here, NaYF4:Er3+ nanoparticles were injected into a small part of isolated pig liver, and heated it with 1550nm infrared laser. At the same time, the laser excited the NaYF4:Er3+ nanoparticles to generate up-conversion green fluorescence. The fluorescence intensity ratio was used to measure the temperature of the heating part in real time.
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