Abstract
Hypothesis: Neonatal computerised trend monitoring (CTM) reduces the morbidity and mortality of infants receiving intensive care.Study type/Setting: Prospective cohort study in a tertiary neonatal service.Patients/Interventions: 445 conseculive newborn who required neonatal intensive care were randomised to receive CTM in addition to the use of conventional monitors (CM) or just CM. The CTM provides a graphical trend over time periods varying from 6 mins to 3 days for any combination (to a maximum of 5) of the monitored physiological or environmental parameters.Measurements: The following short term measures were compared daily over the first 7 days of life - periventricular haemorrhage (with grade - G (out of 4), flares - F (+/-), cysts - C (+/-) and ventricular size - VS (mms); doppler of the anterior cerebral artery - Rl; volume of colloid support - Vol (mls), and number of blood gases performed - BG (n). The outcome measures were death - D, abnormal ultrasound - US, percent discharged home D/C, time to death/discharge - tD/C (d), time ventilated - tV (d) and time in oxygen - tO2(d).Means/medians given as appropriate. Chi2 for categorised outcomes, Wilcoxon for quantitative outcomes and unpaired t test tor short term measures - all NSConclusions: CTM introduced into the management of intensive care neonates could not be demonstrated to improve short term outcome.
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