Abstract

Background: Fighting resistant melasma is a challenge today because the assets used have some limitations as they are irritating, photosensitive and melanocitotoxic, such hydroquinone. Cysteamine is a safe and potential asset for the treatment of resistant melasma as being a natural product of L-cysteine metabolism. Because it contains a thiol group, it has an offensive odor which makes its use in dermocosmetics difficult. The aim of the present study was to evaluate efficacy of a cream gel containing cysteamine with odor softening complex in the treatment of melasma.

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