1539 IS IIEF-EF A PROXY OF GENERAL MALE HEALTH STATUS?

Abstract

You have accessJournal of UrologySexual Function/Dysfunction/Andrology: Evaluation1 Apr 20111539 IS IIEF-EF A PROXY OF GENERAL MALE HEALTH STATUS? Andrea Salonia, Antonino Saccà, Matteo Ferrari, Umberto Capitanio, Rayan Matloob, Fabio Castiglione, Lorenzo Rocchini, Giuseppe Zanni, Luigi Barbieri, Renzo Colombo, Patrizio Rigatti, and Francesco Montorsi Andrea SaloniaAndrea Salonia milan, Italy More articles by this author , Antonino SaccàAntonino Saccà milan, Italy More articles by this author , Matteo FerrariMatteo Ferrari milan, Italy More articles by this author , Umberto CapitanioUmberto Capitanio milan, Italy More articles by this author , Rayan MatloobRayan Matloob milan, Italy More articles by this author , Fabio CastiglioneFabio Castiglione milan, Italy More articles by this author , Lorenzo RocchiniLorenzo Rocchini milan, Italy More articles by this author , Giuseppe ZanniGiuseppe Zanni milan, Italy More articles by this author , Luigi BarbieriLuigi Barbieri milan, Italy More articles by this author , Renzo ColomboRenzo Colombo milan, Italy More articles by this author , Patrizio RigattiPatrizio Rigatti milan, Italy More articles by this author , and Francesco MontorsiFrancesco Montorsi milan, Italy More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2011.02.1534AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES To assess whether erectile function [as defined with the IIEF-erectile function domain score (IIEF-EF)] is associated with health-significant comorbidities scored with the Charlson Comorbidity Index (CCI). METHODS Clinical and ultrasound variables of the last 100 consecutive patients who underwent penile duplex Doppler ultrasounds performed for erectile dysfunction (ED) at a single Institution by 3 expert technicians (ie, each performing >50 evaluations per year) were considered. Patients were comprehensively assessed with a detailed medical and sexual history, including data on duration of ED, ED severity (as defined with the IIEF-EF). As a proxy of general health status, we scored health-significant comorbidities with the CCI. Descriptive statistics and either logistic or linear regression models tested the association between clinical and ultrasounds variables and CCI. CCI was included in the model both as continuous and categorized variable (namely, 0 vs. ≥1). RESULTS Complete data were available for 99 (99%) [mean (SD) age: 45.9 (13.2) yr; range: 23–75; BMI: 26.7 (6.9); CCI: 0.6 (1.08); range: 0–5; CCI≥1: 35/99 (35.4%)] patients. Mean ED duration was 3.7 (4.7) yr. Mean IIEF-EF was 12.9 (9.3); according to IIEF-EF, patients had no ED, mild ED, mild-to-moderate ED, moderate ED, and severe ED in 9 (9.1%), 20 (20.2%), 9 (9.1%), 16 (16.2%), and 45 (45.5%) patients, respectively. The linear regression analysis showed that CCI linearly increased with ageing (Beta 0.33; p=0.001) and linearly decreased with IIEF-EF (Beta −0.25; p=0.01). Acceleration time parameters were also inversely associated with CCI (all Beta −0.31; all p≤0.04). No clear linear association emerged between BMI, PSV and RI and CCI. At logistic regression analysis age (OR=1.05; p=0.004) and IIEF-EF (OR=0.95; p=0.04) were significantly associated with categorized CCI, after accounting for all other variables. CONCLUSIONS Severity of ED, as objectively interpreted with IIEF-EF, emerged as a significant proxy of general male health status. © 2011 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 185Issue 4SApril 2011Page: e618 Advertisement Copyright & Permissions© 2011 by American Urological Association Education and Research, Inc.MetricsAuthor Information Andrea Salonia milan, Italy More articles by this author Antonino Saccà milan, Italy More articles by this author Matteo Ferrari milan, Italy More articles by this author Umberto Capitanio milan, Italy More articles by this author Rayan Matloob milan, Italy More articles by this author Fabio Castiglione milan, Italy More articles by this author Lorenzo Rocchini milan, Italy More articles by this author Giuseppe Zanni milan, Italy More articles by this author Luigi Barbieri milan, Italy More articles by this author Renzo Colombo milan, Italy More articles by this author Patrizio Rigatti milan, Italy More articles by this author Francesco Montorsi milan, Italy More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...