1536 Egfl6 induces IL-10 and CXCL2 in tumor associated myeloid cells: link to anti-tumor immunosuppression and resistance to anti-PD-L1 therapy in ovarian cancer

Abstract

BackgroundMyeloid-derived suppressor cells (MDSCs) and tumor-associated macrophages (TAMs) are critical negative regulators of immunity in cancer.1 2 Understanding factors which regulate these cells could result in the identification of new...