Abstract

Previous studies have shown that adding immune checkpoint inhibitor (ICI) to chemotherapy for extensive-stage small cell lung cancer (ES-SCLC) is effective and is currently the first-line treatment. However, there is no evidence whether it is effective as a second-line treatment after first-line chemotherapy and ICI combination therapy. Amrubicin is recommended as a second-line treatment for ES-SCLC in the guideline, and it is frequently used in Japan. Here, we report a retrospective study on the efficacy and safety of amrubicin as a second-line treatment for ES-SCLC after ICI therapy.

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