153 The experience of the largest greek maternity hospital during the COVID-19 pandemic

Abstract

Introduction and aims of the study: The objective of our study is to report the impact of Covid-19 infection during pregnancy to maternal and neonatal outcomes. Methods: We documented the medical records of all pregnant women who were admitted to “Alexandra” maternity hospital in Athens, Greece from March 2020 to March 2021 and tested positive for SARS-CoV-2 (n=85). A nasopharyngeal swab specimen was collected from all pregnant women who were admitted to hospital during the pandemic and evaluated for Covid-19 infection via real-time polymerase chain reaction (RT-PCR). The demographic data, clinical status, laboratory values, pregnancy characteristics, maternal and fetal outcomes were documented for all SARS-CoV-2 positive pregnant women. Results: During the study period a total of 85 pregnant women positive for Covid-19 were admitted to our department. Gestational age (GA) of pregnancy during admission ranged from 7 to 42 weeks of gestation. Mean maternal age was 29.6 years. Patient history revealed comorbidities such as hypertension, hypothyroidism, epilepsy, thrombophilia, hepatitis B and asthma. Sixty-seven out of eighty-five pregnant women delivered within the study period. Cesarean section was performed in 59.7% of the cases. The majority of cases (77.7%) were asymptomatic during admission and remained asymptomatic during the course of their hospitalization while three patients required invasive ventilation. All neonates tested negative for SARS-CoV-2. Neither maternal nor neonatal deaths occurred in the study population. Conclusions: In accordance with recent published studies, our experience delineates the mild course of SARS-CoV-2 infection during pregnancy in the majority of cases. At the same time, neonatal outcomes appear favorable as well. However, further studies are warranted as increased severity of COVID-19 infection during pregnancy and sporadic cases of intrauterine growth restriction have also been reported.