Abstract
The skin forms an interface between the body and the environment and provides distinct niches for microbial communities. Next-generation-sequencing used to characterize the cutaneous microbiome in psoriasis patients revealed an over-representation of Proteobacteria and a reduction of Actinobacteria in lesional skin, suggesting that the development of psoriatic plaques might be linked to specific alterations in the cutaneous microbiome and successful treatment could help to normalize the microbiome even before clinical parameters improve.
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