Abstract
Background: According to the Centers for Disease Control and Prevention 2015 sexual transmitted disease treatment guidelines, Benzathine penicillin G (BPG) is the recommended first-line treatment for the treatment of syphilis. In our general practice, using lidocaine as the diluent of BPG causes pain at the injection sites. This study aimed to compare the effect of BPG diluted in 1% lidocaine versus that diluted in sterile water on injection sites.
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