1511 MID-TERM FOLLOW-UP ON THE EFFECT OF LOW INTENSITY SHOCK WAVES FOR THE TREATMENT OF ERECTILE DYSFUNCTION

Abstract

You have accessJournal of UrologySexual Function/Dysfunction/Andrology: Medical and Nonsurgical Therapy1 Apr 20131511 MID-TERM FOLLOW-UP ON THE EFFECT OF LOW INTENSITY SHOCK WAVES FOR THE TREATMENT OF ERECTILE DYSFUNCTION Ilan Gruenwald, Boaz Appel, Omar Massarwi, and Yoram Vardi Ilan GruenwaldIlan Gruenwald Haifa, Israel More articles by this author , Boaz AppelBoaz Appel Haifa, Israel More articles by this author , Omar MassarwiOmar Massarwi Haifa, Israel More articles by this author , and Yoram VardiYoram Vardi Haifa, Israel More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2013.02.2989AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Our aim was to evaluate the overall mid-term efficacy (6 months) of penile Low Intensity Shock Wave therapy (LI-ESWT) in patients who participated in different studies regardless of ED severity, response to PDE5i, and etiology of ED. METHODS During the past 30 months we have followed up and evaluated the efficacy of LI-ESWT on 191 ED patients (155 treated and 36 Sham). These subjects represent various degrees of ED severity and response to PDE5i therapy. All received the same treatment protocol but participated in different trials. Follow- up data were collected at the 6 month period after end of treatment and were compared to the patients' baseline scores before treatment. RESULTS Mean age was 59± 10.3 and Mean ED Duration was 65.1 months. 86.4% were cardiovascular patients, 61 (40%) were diabetic of which 50.81% had a significant clinical improvement. The mean baseline IIEF-EF domain scores were 11.0 (and mean baseline total IIEF scor was 34.48. Based on changes in IIEF-EF Domain scores, 57.4% of all males had a significant clinical mprovement 6 months after therapy. Categorizing them to severe, moderate and mild ED groups showed that 52%, 65% and 79% improved respectively according to the newly defined minimal clinical improvement criteria. Thirty two percent of the mild group reached normalization, while 24% and 15% of the moderate and severe group reached normalization respectively. CONCLUSIONS In this study we have demonstrated that applying LI-ESWT directly to the penis has a significant clinical effect for all ED severities, for cardiovascular and diabetic patients as well as for either responders or non- responders to PDE5i therapy. This study also showed that the clinical effect is maintained at least for a 6 month period. Further follow up on a larger scale of ED populations is necessary in order to fully evaluate the long term or permanent effect of this treatment modality. © 2013 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 189Issue 4SApril 2013Page: e619 Advertisement Copyright & Permissions© 2013 by American Urological Association Education and Research, Inc.MetricsAuthor Information Ilan Gruenwald Haifa, Israel More articles by this author Boaz Appel Haifa, Israel More articles by this author Omar Massarwi Haifa, Israel More articles by this author Yoram Vardi Haifa, Israel More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...