1504P Real-world treatment patterns and outcomes of metastatic synovial sarcoma over the last decade in England

Abstract

Synovial Sarcoma (SS) is a rare and biologically aggressive - generally considered high-grade - soft tissue sarcoma. With an annual incidence of 1.4 cases per million in the UK, the prognosis for SS patients is poor. There is no established standard of care for metastatic SS (mSS) beyond 1st line of therapy (LoT). This real-world study aimed to be the first to contextualise the therapeutic landscape and survival outcomes of mSS patients in England using the Cancer Analysis System, a population-level cancer database.