Abstract
Pemphigus is an autoimmune blistering disease that causes painful erosions, while bullous pemphigoid (BP) is classically known to cause pruritic blisters. Previous reports and anecdotal clinical observations suggest pemphigus patients also experience significant itch; we explored the prevalence and potential predictors of itch in pemphigus patients compared with BP. While the Bullous Pemphigoid Disease Area Index (BPDAI) has a subjective patient itch score (0-10 over 24 hours, week, and month), the Pemphigus Disease Area Index (PDAI) does not, so the BPDAI Pruritus component was administered to both BP and pemphigus patients.
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