Abstract
AbstractThis review describes cross-dehydrogenative coupling (CDC) reactions used for the synthesis of natural products and active pharmaceutical ingredients (APIs). CDC reactions generally streamline the synthesis of multifunctional molecules because they do not require preactivation or prefunctionalization of the substrates. C(sp2)—C(sp2), C(sp2)—C(sp3), and C(sp3)—C(sp3) bond-forming CDC reactions through Fujiwara–Moritani reaction, Friedel–Crafts-type reactions, Minisci-type reactions, and enolate coupling reactions are summarized.
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