Abstract
Tumor cells have a tendency to proliferate rapidly and can metastasize to other organs of the body. Respiratory carcinomas are among 3rd predominant causes of cancer-related deaths in both genders around the globe. Type of epithelial lung cancer non-small cell lung carcinoma (NSCLC) constitutes 80% of all lung cancer types. The 5-year survival rate of NSCLC is about 16%. This Study was conducted to understand the chemoresistance through expression of proto-onco genes (AKT1, ALK), onco-suppressive (FBXW7, PTEN) genes and their correlation with miRNA 140-145 in NSCLC.
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