149P Can high Ki67 predict distant recurrence in early stage breast cancer with low oncotype Dx score?

Abstract

Oncotype Dx recurrence score provides prognostic and predictive information for recurrence in early stage breast cancer. Patients with low oncotype Dx scores (=<25) are less likely to recur and often adjuvant chemotherapy is not necessary. However, a small minority of patients with low Oncotype Dx scores will experience recurrence. In this retrospective study, we examined whether high Ki67 could predict the distant recurrence in early stage breast cancer with low oncotype Dx scores.