Abstract
Recent reports suggest that elevated urinary LDH isoenzyme 5 activity is a reliable tool to separate upper from lower urinary tract infection. Total urinary LDH enzyme activity and isoenzyme activity were performed in urine from 52 episodes of urinary tract infection studied with the bladder washout technique. The technique for LDH determination includes dialyzing the urine, concentrating it and electrophoresis on cellulose acetate. Thirty-seven infections were localized by bladder washout to the lower tract and 15 to the upper tract. Urines from 33 girls without urinary infection were also analyzed for LDH. There was a significant difference between the total LDH enzyme activity from the “control” group compared with the groups with urinary infection. However, neither total LDH nor % LDH isoenzyme 5 served to distinguish lower from upper tract infection. The marked variations in the total LDH enzyme activity as well as the % of urinary LDH isoenzyme 5 activity are evident in the large standard deviation of the mean values derived from both control and infected subjects. Urinary LDH enzyme activity and percentage LDH isoenzyme 5 do not appear to separate upper from lower urinary tract infections.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
