Abstract
Introduction: Hidradenitis suppurativa (HS) is a chronic, inflammatory disease characterized by painful nodules, abscesses and draining sinuses, most commonly occurring in the inguinal, axillary, and submammary areas. Severe disease is associated with discharging sinus tracts and fibrotic scarring. The development of dermal tunnels and interconnecting tracts is poorly understood, and has traditionally been considered an end-stage feature of disease. Methods/Results: After receiving approval from the Rockefeller University’s Institutional Review Board, unaffected, perilesional and lesional HS skin was collected by punch biopsies.
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