Abstract
Tumor microenvironment plays a crucial role in cancer development and tumor-associated macrophages (TAMs) are emerging as key players. Nevertheless, TAMs role in advanced Gastric Cancer (GC) need to be further clarified. The inability of lymphocytes to reach tumor cells is an important mechanism of treatment resistance and cancer exclusion of CD8 T cells is correlated with a poor clinical outcome. Macrophages contribute to lymphocyte trapping by long-lasting interactions with CD8 T cells that causes immunosuppression and poor outcome.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
