1473 Laparoscopic Sacrocolpopexy Plus Colporrhaphy with an Sis Graft Versus Total Pelvic Floor Reconstruction for Advanced Prolapse: A Retrospective Cohort Study

Abstract

Study Objective Transvaginal mesh (TVM) results in a greater anatomic cure but more complications. We aimed to compare laparoscopic sacrocolpopexy (LSC) plus colporrhaphy with a small intestine submucosa (SIS) graft versus TVM for advanced pelvic organ prolapse (POP). Design Retrospective study, with more than one year follow-up. Setting Tertiary university-affiliated hospital. Patients or Participants Between September 2015 and November 2016, 76 patients with advanced POP who underwent LSC plus colporrhaphy with an SIS graft or TVM. Interventions LSC plus colporrhaphy with an SIS graft or TVM. Measurements and Main Results Data regarding surgical procedures and patient demographic variables were recorded. Anatomical outcomes were evaluated using POP quantification (POP-Q). Functional outcomes related to POP and sexual life were evaluated using the Pelvic Floor Distress Inventory (PFDI-20) and the Pelvic Floor Impact Questionnaire (PFIQ-7). Chi-squared and Student's t-tests were used for two independent samples. 76 patients were enrolled in this study with 26 patients in the LSC plus colporrhaphy with an SIS graft group (group A) and 50 patients with TVM group (group B). All patients in both groups demonstrated significant improvement in anatomical outcomes (p Conclusion Even though both surgeries showed excellent results for subjective and objective outcomes, the use of an SIS graft might increase the exposure of mesh. We do not recommend LSC plus colporrhaphy with an SIS graft for advanced multiple-compartments prolapse.