Abstract

assay (ELISA) kits (IBEX & Nordic Bioscience). Relationships between ratios of degradation to synthesis markers and JSW-D were evaluated using analysis of covariance (ANCOVA). Results: All data were all transformed (via square root or natural log) to normalize distributions. Covariates including baseline age, sex, BMI, and time since baseline evaluation were retained in ANCOVA models if they were found to have p-values >0.2. Transformed mean & median concentrations as well as p-values for degradation to synthesis ratios are presented in Table 1.

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