1464-P: Trends in Prevalence of Youth-Onset Type 1 and Type 2 Diabetes, 2001-2017: The SEARCH for Diabetes in Youth Study

Abstract

Objective: To estimate change in prevalence of type 1 (T1D) and type 2 diabetes (T2D) among U.S. youth (<20 yrs.) from 2001 to 2017. Methods: Diabetes cases prevalent in 2001, 2009 and 2017 were identified in geographic areas (Colorado, Ohio, South Carolina, Washington) and among managed health care members (California). Similar methods were used in each year. Prevalence (cases/1,000 youth) of physician-diagnosed T1D (0-19 years) and T2D (10-19 years) were calculated for each year. Population denominators were obtained from U.S. census data and membership counts. Race/ethnicity was categorized as non-Hispanic white (NHW), Hispanic (HSP), African American (AA), Asian/Pacific Islander (API) and American Indian (AI). Differences in proportions and annual percent change (APC) with 95% confidence intervals are reported. Results: From 2001 to 2017, prevalence increased from 1.5 to 2.2/1,000 for T1D and from 0.3 to 0.7/1,000 for T2D (Table). Significant increases (p<0.05) in T1D and T2D were observed in each race/ethnicity group except T2D among AI (p=0.06). The greatest increases in T1D were among NHW and NHB and for T2D, among NHB, HSP, and API. APC was similar by sex within diabetes type. Conclusions: While the prevalence of T1D is higher than youth-onset T2D, the APC is almost double for T2D. Efforts to identify and mitigate risk factors for onset of T1D and T2D remain vital public health priorities. Disclosure J.M. Lawrence: None. A.D. Liese: None. S. Saydah: None. G. Imperatore: None. E.T. Jensen: None. E.J. Mayer-Davis: None. D. Dabelea: None. D.J. Pettitt: None. S.M. Marcovina: None. C. Pihoker: None. L.M. Dolan: None. S. Isom: None. J. Divers: None. Funding Centers for Disease Control and Prevention; National Institute of Diabetes and Digestive and Kidney Diseases (1U18DP006131, U18DP006133, U18DP006134, U18DP006136, U18DP006138, U18DP006139)