146 Promising tools to facilitate the implementation of TDM of biologics in clinical practice

Abstract

Therapeutic drug monitoring (TDM) of biologics - encompassing the measurement of (trough) concentrations and anti-drug antibodies - is emerging as a valuable tool for clinical decision-making. While this strategy needs further validation, attention for its implementation into the clinic is warranted. Rapid testing and easy sampling are key to its implementation. Here, we aimed to evaluate the feasibility and volunteers’ perception of home microsampling for quantification of adalimumab (ADM) concentrations in psoriasis patients.