Abstract

Waist circumference (WC) is currently one of the components of metabolic syndrome (MetS) , but the cutoff points of WC for diagnosing MetS vary between races and genders. Therefore, the aim of this study is to search an anthropometric indicator instead of WC that would be applicable across races and genders. Our previous study found that a waist-to-height ratio (WHtR) >= 0.52 has excellent diagnostic value for MetS in both men and women with type 2 diabetes mellitus (T2DM) . We therefore selected 8525 T2DM patients with complete clinical data in the present study. Agreement between a WHtR >= 0.52 and different WC diagnostic criteria for men (>=90cm) and women (>=80cm) was almost perfect (Kappa=0.911) . As a component of MetS instead of WC, the AUC of new criteria using WHtR to diagnose MetS was 0.963 in T2DM patients. Using a WHtR cut-off of 0.52 most closely associated with the prevalence of MetS in man (98.0% sensitivity and 94.7% specificity) and women (95.7% sensitivity and 98.0% specificity) participants and. Taken together, the use of WHtR instead of WC is a simple and practical indicator for the diagnosis of MetS in T2DM. Disclosure J.Ke: None. J.Wang: None. Y.Ma: None. Y.Wang: None. L.Li: None. Funding National Natural Science Foundation of China (81770813, and 82070866) .

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