1422: Ultrasound-Guided Fine Needle Aspiration Cytology of the Salivary Gland: A Review of 258 Cases

Abstract

ObjectiveTo evaluate the diagnostic accuracy and pitfalls of ultrasound-guided fine needle aspiration (US-FNA) for salivary gland lesions.MethodsTwo hundred and fifty-eight US-FNA cytology specimens of salivary gland lesions taken over a 4-year period were reviewed and correlated with the histopathological findings obtained from surgical specimen. The aspirates were derived from parotid gland (218 cases) and submandibular gland (40 cases).ResultsThe major diagnostic categories for cytology were unsatisfactory (34 cases), non-neoplastic lesions (17 cases), benign neoplasm (180 cases), and malignant neoplasm (27 cases). Final pathological review showed that 172 of 192 (90%) benign tumors and 27 of 48 (56%) malignant tumors with adequate US-FNA sampling were accurately diagnosed cytologically. False-negative results were caused by sampling error (11 cases) or misinterpretation of uncommon tumors (10 cases). The overall sensitivity, specificity and accuracy of US-FNA were 83%, 96%, and 90%, respectively.ConclusionUS-FNA cytology is reliable in distinguishing benign and malignant salivary gland tumors and provides accurate diagnosis of most salivary gland lesions. ObjectiveTo evaluate the diagnostic accuracy and pitfalls of ultrasound-guided fine needle aspiration (US-FNA) for salivary gland lesions. To evaluate the diagnostic accuracy and pitfalls of ultrasound-guided fine needle aspiration (US-FNA) for salivary gland lesions. MethodsTwo hundred and fifty-eight US-FNA cytology specimens of salivary gland lesions taken over a 4-year period were reviewed and correlated with the histopathological findings obtained from surgical specimen. The aspirates were derived from parotid gland (218 cases) and submandibular gland (40 cases). Two hundred and fifty-eight US-FNA cytology specimens of salivary gland lesions taken over a 4-year period were reviewed and correlated with the histopathological findings obtained from surgical specimen. The aspirates were derived from parotid gland (218 cases) and submandibular gland (40 cases). ResultsThe major diagnostic categories for cytology were unsatisfactory (34 cases), non-neoplastic lesions (17 cases), benign neoplasm (180 cases), and malignant neoplasm (27 cases). Final pathological review showed that 172 of 192 (90%) benign tumors and 27 of 48 (56%) malignant tumors with adequate US-FNA sampling were accurately diagnosed cytologically. False-negative results were caused by sampling error (11 cases) or misinterpretation of uncommon tumors (10 cases). The overall sensitivity, specificity and accuracy of US-FNA were 83%, 96%, and 90%, respectively. The major diagnostic categories for cytology were unsatisfactory (34 cases), non-neoplastic lesions (17 cases), benign neoplasm (180 cases), and malignant neoplasm (27 cases). Final pathological review showed that 172 of 192 (90%) benign tumors and 27 of 48 (56%) malignant tumors with adequate US-FNA sampling were accurately diagnosed cytologically. False-negative results were caused by sampling error (11 cases) or misinterpretation of uncommon tumors (10 cases). The overall sensitivity, specificity and accuracy of US-FNA were 83%, 96%, and 90%, respectively. ConclusionUS-FNA cytology is reliable in distinguishing benign and malignant salivary gland tumors and provides accurate diagnosis of most salivary gland lesions. US-FNA cytology is reliable in distinguishing benign and malignant salivary gland tumors and provides accurate diagnosis of most salivary gland lesions.