Abstract
ABSTRACT Background There is consensus that heavy alcohol drinking is related to increased risk of several cancer types. However, the role of light-moderate drinking and the existence of a threshold amount of alcohol for risk are less clear. Methods We exploredpossible underreporting among moderate drinkers in a cohort study of 129,987 persons. From baseline in 1978-85 through 2008 cancer was diagnosed in 15,080 persons. Cox proportional hazard models were controlled for age, sex, ethnicity, smoking, education, and body mass index. Alcohol was studied categorically, with lifelong abstainers as referent. We studied risk of any cancer and of a composite of 5 types with alcohol-associated risk in this cohort (upper airway digestive, liver, breast, lung, colo-rectal). We stratified moderate drinking categories ( Results The relative risks (RR) and 95% confidence intervals (CI) among the alcohol categories for any cancer were: exdrinkers = 1.17 (1.07-1.27, p Conclusions We conclude that apparent increased risk of cancer among light-moderate drinkers is substantially due to underreporting of intake. Disclosure All authors have declared no conflicts of interest.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
