Abstract

Ovarian cancer (OC) is one of the leading causes of cancer-related deaths in women both in Asia and worldwide. The NCCN guidelines suggest all newly diagnosed OC patients should take genetic risk evaluation including BRCA1/2 testing. OC patients who have deleterious BRCA1/2 variants are likely to benefit from PARP inhibitors. We aimed to investigate the prevalence and characteristics of BRCA1/2 mutations in Chinese OC patients.

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