140 Ameloblastom Olgusunun Klinik ve Histolojik Analizi: Histolojik Varyantların Değerlendirilmesi

Abstract

Objektive: The objective of this study is to evaluate the clinical and demographic features of ameloblastoma cases of a pathology center with a detailed examination of the histopathological properties of the subtypes and variants. Material and Methods: The clinical and radiological data and histologic slides of ameloblastoma cases diagnosed and treated between 2005 and 2017 were retrieved from the archives. Histopathological features of previously diagnosed cases were re-evaluated and re-classification of all cases was performed in accordance with the World Health Organization (WHO) classification of odontogenic tumors. The significance of the relationship between radiological appearance (multiocularity/unilocularity) and final histological diagnosis (solid/unicystic) was evaluated with statistical analysis. Results: There were a total of a hundred and forty cases of ameloblastoma. A hundred and twenty (85.7%) cases were diagnosed as solid type. Sixteen (11.4%) cases were diagnosed as unilocular ameloblastoma. Three cases showed admixed histopathological characteristics. There was a significant relationship between radiological appearance and histological diagnosis (p=0.005). All recurrent luminal unicystic ameloblastomas were re-diagnosed as mural subtype in the histopathological examination. Conclusion: The presence of rare variants should be diagnosed correctly with a thorough histopathological examination to contribute to the prognosis. The radiographic appearance of the tumor is correlated with the histological subtype. In the examination of recurrent unicystic cases, the surgical specimen should be entirely inspected to indicate mural ameloblastic invasions.