Abstract
Bovine Spongiform Encephalopathy (BSE) is a progressive degenerative disease that affects the Central Nervous System (CNS) of adult cattle. BSE has since been confirmed in 21 other countries in Europe plus Japan, Israel, Canada, and the USA. The agent that causes BSE has not been fully characterized but is believed, by most in the scientific community, to be an abnormal form of a normal, cellular, prion protein that is found in mammalian animals. The scientific community believes BSE moved from cattle to humans when infected meat was cut up, ground or processed, and consumed by people. This chapter discusses the rationale for removal and handling of BSE Specified Risk Material (SRM) in the UK, the EU, the USA, Canada, and Japan. There are differences in logic regarding what constitutes SRM among countries (for example, age-intersects, amount of intestine required to be removed, use of “dedicated tools/equipment”). These differences are, in large part, a result of government officials interpreting relative risk in the light of the incidence of BSE cases that have occurred in their respective countries.
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