14 Incidence and phenotype at diagnosis in paediatric IBD patients – An ECCO-EpiCom study

Abstract

s of the 8th Congress of ECCO the European Crohn’s and Colitis Organisation S7 were unchanged in a sensitivity analysis including only patients in whom we had Hb data from all four visits (data not shown). Women with CD had a higher prevalence of anemia than men with CD at the ten year follow-up (20% vs 7.3%, p = 0.018) (Figure 1). Conclusions: Anemia is more common in CD than in UC. The prevalence of anemia decreases during the disease course. Women with CD are at high risk for anemia even after ten years of disease. 14 Incidence and phenotype at diagnosis in paediatric IBD patients An ECCO-EpiCom study J. Burisch1 *, D. Duricova2, N. Pedersen1, R. Salupere3, E. Tsianos4, M. Martinato5, O. Tighineanu6, V. Hernandez7, P. Lakatos8, P. Munkholm1, On behalf of the EpiCom Northern Italy center based in Crema, Cremona, Firenze, Forli, Padova and Reggio Emilia, Italy. 1Herlev University Hospital, Department of Gastroenterology, Copenhagen, Denmark, 2Charles University, IBD Center ISCARE, Prague, Czech Republic, 3Tartu University Hospital, Division of Endocrinology and Gastroenterology, Tartu, Estonia, 4University Hospital, 1st Division of Internal Medicine and Hepato-Gastroenterology Unit, Ioannina, Greece, 5On behalf of the EpiCom Northern Italy center based in Crema, Cremona, Firenze, Forli, Padova and Reggio Emilia, Italy, 6Center of Mother and Child, Section of Pediatric Gastroenterology, Chisinau, Republic of Moldova, 7Complexo Hospitalario Universitario de Vigo, Gastroenterology Department, Vigo, Spain, 8Semmelweis University, 1st Department of Medicine, Budapest, Hungary Background: The incidence of inflammatory bowel disease (IBD) is traditionally low in Eastern Europe. It has however recently become more prevalent in i.e. Hungary and Croatia. Furthermore, the incidence of paediatric IBD is increasing [1]. The reason for these changes remains unknown. The EpiComstudy was initiated in 31 centres from 14 Western and 8 Eastern European countries to investigate the differences in incidence and phenotype at diagnosis in Europe. 9 centres included paediatric patients. Methods: A prospective, population-based, uniformly diagnosed by international diagnostic criteria, inception cohort of patients diagnosed with IBD within 1.1.2010 31.12.2010 and followed up until 1.1.2012 was created. Patients were entered in a web-based database, www.epicom-ecco.eu. Disease localization and behaviour was classified according to the Montreal classification. Table 1. Incidence of IBD (UC/CD/IBDU) in Europe Centre Incidence No. of patients