Abstract
AbstractNitration of 2‐amino‐4‐oxo‐(3H)‐5‐trifluoromethylquinazoline is shown to occur exclusively at C6 as determined from an analysis of long range 1H and 19F scalar couplings to ring carbons. Nitration of 2‐amino‐4‐oxo‐(3H)‐5‐fluoroquinazoline is found to occur both at C6 and C8 as evident from an analysis of the 19F and 1H couplings of the ring protons.
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