Abstract

Overall survival (OS) is the standard endpoint in oncology trials but often requires prolonged follow-up. Event-free survival (EFS) is a well-accepted endpoint in early-stage oncology trials and a common surrogate endpoint for OS in neoadjuvant and adjuvant cancer therapy. This study aims to evaluate the trial-level association between EFS and OS for patients with gastric or gastroesophageal junction (GEJ) adenocarcinoma in neoadjuvant/adjuvant settings.

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