1380 LONG-TERM INFECTION OUTCOMES AFTER HYDROPHILIC COATED INFLATABLE PENILE PROSTHESIS IMPLANTS: 11 YEARS OF FOLLOW-UP

Abstract

You have accessJournal of UrologySexual Function/Dysfunction/Andrology: Evaluation II1 Apr 20121380 LONG-TERM INFECTION OUTCOMES AFTER HYDROPHILIC COATED INFLATABLE PENILE PROSTHESIS IMPLANTS: 11 YEARS OF FOLLOW-UP Ege Can Serefoglu, Sree Harsha Mandava, Ahmet Gokce, and Wayne J.G. Hellstrom Ege Can SerefogluEge Can Serefoglu New Orleans, LA More articles by this author , Sree Harsha MandavaSree Harsha Mandava New Orleans, LA More articles by this author , Ahmet GokceAhmet Gokce New Orleans, LA More articles by this author , and Wayne J.G. HellstromWayne J.G. Hellstrom New Orleans, LA More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2012.02.1807AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Penile implant surgery continues to be a positive alternative for patients with severe ED. Historically, adverse events related to infection were 3-4% for original implants. Advancements in technology have contributed to improved efficacy and decreased adverse events, such as infection. This review of 36,391 implants compares the pre/post infection rates after the inclusion of a technological (hydrophilic) coating enhancement between two implantable, three-piece, penile prostheses (IPP), the Mentor Alpha 1® and the Titan® (Coloplast Corp., Minneapolis, MN). METHODS A substantial number of Alpha 1 and Titan implants reported into a volunteer, post-market registry, from July 14, 2000 to Sept 30, 2011 were reviewed and compared with infections reported in the product evaluation database. The advanced Titan includes hydrophilic coating across all components allowing for the absorption of an aqueous solution, while no components of the Alpha 1 employed a hydrophilic coating. Data was analyzed using a Pearson's chi-square test to determine significance of reduction in reported infection between the Alpha IPP and the hydrophilic-coated Titan IPP. RESULTS A total of 7031 implants and 322 infections (4.6%) were reported with the Alpha 1 implant, and 29,360 implants with 402 infections (1.4%) reported with the Titan implant, showing a statistically significant (p-value 0.0001) decrease in reported infections between the Alpha IPP and hydrophilic-coated Titan IPP. CONCLUSIONS New advances in technology continue to improve efficacy and decrease adverse events for patients with severe ED treated with penile implants. Significant decreases in reported infection rates between the non-coated Alpha 1 IPP and the hydrophilic-coated Titan IPP suggest that the technology may contribute to decreased infections. © 2012 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 187Issue 4SApril 2012Page: e560-e561 Advertisement Copyright & Permissions© 2012 by American Urological Association Education and Research, Inc.MetricsAuthor Information Ege Can Serefoglu New Orleans, LA More articles by this author Sree Harsha Mandava New Orleans, LA More articles by this author Ahmet Gokce New Orleans, LA More articles by this author Wayne J.G. Hellstrom New Orleans, LA More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...