Abstract
Recombinant adenovirus vectors continue to be widely used in gene therapy approaches and have demonstrated utility in the study of gene function. With the availability of gene and shRNA collections and the need for efficient delivery into a wide range of cell types, there is now a requirement for rapid and efficient scalability of adenoviral vector production. However, methods for the simultaneous production of multiple adenoviral vectors have been lacking due to cumbersome vector construction via bacterial recombination and purification strategies using cesium chloride.
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