1360P Identification of epidermal growth factor receptor (EGFR) fusions in a large Chinese lung cancer population

Abstract

Next generation sequencing has identified some rare EGFR fusions in lung cancer, such as EGFR-RAD51 and EGFR-SEPT14, which are known to respond to EGFR-TKIs. However, prevalence of EGFR fusions in a large population is unknown yet. Herein, we analyzed a large-scale dataset comprehensively to explore the mutation characteristics of EGFR fusions. This study offered an estimate of the proportion of patients with EGFR fusion who could benefit from therapies.