Abstract
Pure uterine sarcomas are rare tumours which account for less than 3 % of all uterine malignancies. Knowledge about their molecular background is limited. Identification of new molecular pattern and new molecular markers could help to better stratify these tumours in terms of their diagnostic or therapeutic options. Whole transcriptome RNA-Seq is a robust tool which could reveal novel gene fusions, aberrant splicing events, or gene expression. However, optimization of library preparation from archive specimens (FFPE) is crucial for a retrospective study, which is necessary due to the rarity of these tumours.
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