Abstract
Background: Medicinal herbs have been widely used for their anti-obesity effects among women with overweight and obesity. However, evidence showed that using these herbs with various types of phytoestrogens, fatty acids and active components may affect sex hormones and gene expression of parameters related to the prognosis of hormone-related cancers such as BC, especially among obese populations and premenopausal women. One of these medicinal herbs is black seed (BS) which is a major source of kaempferol (a flavonoid phytoestrogen) and fatty acids.
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