Abstract
1. 1. Snails and cockroaches were examined by paper chromatography after 2 to 7 days of treatment with 131I. In both organisms a labeled product was observed which had a mobility similar to that of thyroxine when chromatographed in a collidine-NH 4OH solvent mixture, but did not coincide with thyroxine nor with any of 7 other thyroid hormone derivatives when chromatographed with two other solvent systems. Our findings do not support the view that thyroid hormone synthesis can occur in these invertebrates. 2. 2. It is suggested that the formation of organic 131I in these and other invertebrates is due to the oxidizing action of quinones present as part of a mechanism for the hardening of proteinaceous structural organs .
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