Abstract
Poor air quality in large cities has shown to have a negative effect on human health and to induce skin inflammation and premature aging. Less attention has been paid to rural environments, thus the effects on skin of specific rural pollutants are largely unknown. In addition, the combined effect of rural PM and solar radiation is also of interest. Here we investigate the effects of fine particulate matter (PM2.5) collected from rural environments on interleukin (IL) and matrix metalloprotease (MMP) production in human neonatal keratinocytes in the absence or presence of solar simulated UVR (ssUVR).
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