Abstract
Metabolism is one of the basic features of life and, in several aspects, the evolution of metabolism certainly precedes the origin of cellular life forms. Focusing mainly on the evolution of exemplary special metabolite biosynthesis pathways in fungi, in this overview the biochemical and genetical mechanics and mechanisms underlying the existing ramifications are described and explained at the current level of understanding. Special attention is given to the evolution of proteins and metabolite function and the evolution of mechanisms to acquire, preserve, and maintain favourable traits within a given lineage. Within the latter field, such topics as gene coupling in functional linkage groups and the roles played by horizontal gene transfer and adaptive evolution are also addressed.
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