Abstract
151 consecutive newborn infants 50, peak inflation pressure >25 cm H2O and 1:E ratio > 1:1. The only factor significantly related to SEH/IVH in SGA infants was the occurrence of alveolar rupture. 14/20 AGA infants and 16/20 SGA infants with alveolar rupture had SEH/IVH. SGA infants appear to be at higher risk of SEH/IVH than AGA infants. The occurrence of SEH/IVH in the preterm SGA infant may be on a different basis than in the AGA infant and related to prenatal nutritional status rather than postnatal iatrogenic events. Prenatal or intrapartum events superimposed upon decreased supportive tissue in the germinal matrix of the SGA infant may play an important role in the evolution of SEH/IVH in the preterm SGA infant.
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