Abstract

Factors involved in non-small cell lung cancer (NSCLC) recurrence remain to be elucidated. Previous studies have revealed that the premalignant process in the small bronchi distant from the tumor is associated with NSCLC progression: patients with basal cell hyperplasia (BCH) more often have distant metastases, whereas patients with BCH combined with squamous metaplasia (SM) predominantly show locoregional relapses. The molecular mechanisms of this association are still not understood. Here, we aimed to assess the mutational landscape of NSCLC in patients with different premalignant bronchial lesions.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.