127 Characterization of bacteria isolated from the respiratory tract of pediatric cystic fibrosis patients followed in a CF specialized center

Abstract

Objectives: Respiratory infections occur early in life of patients with Cystic Fibrosis (CF). Bacterial respiratory colonization has been associated with increased morbidity and mortality in these patients. This study aims to evaluate the prevalence of bacteria isolated from the respiratory tract in patients followed at a Specialized Center of CF (Lisbon) in the last 5 years. Methods: Retrospective analysis of patients followed in the CF Center, between 2008 and 2012. Epidemiological and bacteriological data were evaluated. Conclusion: Sixty four patients (34 females) were evaluated with a median age of 11 years. MSSA was the most frequently isolated bacteria during the five years of the study, followed by PA. In general, 2012 was the year with lower prevalence of chronic colonization by pathogenic bacteria. The exceptions were two bacteria of uncertain clinical significance (SM and AX) (see table). Segregation of patients by colonization was strictly followed. The rate of patients taking inhaled AB was maintained over the time.