126P Effects of GnRHa on ovarian function against chemotherapy-induced gonadotoxicity in premenopausal women with breast cancer in China: A prospective randomized controlled trial (EGOFACT)

Abstract

Premature ovarian insufficiency (POI) is a common toxic effect of chemotherapy in premenopausal female patients. Studies of the use of gonadotropin-releasing hormone analogs (GnRHa) to protect ovarian function have shown mixed results. There has never been any randomized controlled study data on Chinese patients.