Abstract

Abstract Aim Congenital limb absence, the absence of one or more limbs present at birth, is a rare but potentially debilitating condition. Previous research has suggested that there may be a relationship between eye dominance and the development of congenital limb absence, but this relationship has not been extensively studied. In the general population, 35-56% of left handers are left-eye dominant and 62-73% of right handers are right-eye dominant. The aim of this retrospective study is to explore the relationship between eye dominance and congenital limb absence. Method Medical records of individuals with congenital limb absence from between May 1995 and March 2002 were reviewed, and eye dominance was determined through the use of standardized eye dominance tests. A multivariable logistic regression was developed to determine the effect of limb deficiency laterality on eye-dominance. Results A total of 81 patients were eligible for inclusion in the study with a median age of 25 (IQR = 20). 54.3% (n = 44) of the patients were female. Laterality of limb absence was 27:54 (Left:Right). In our study group, 81.5% of left-hand dominant patients were left eye dominant. 83.3% of right-hand dominant patients were right eye dominant. Patients were more likely to be right eye dominant than left eye dominant (OR 22.39, 7.02-85.80, p<0.001). Conclusions This study suggests that there may be a potential link between eye dominance and the development of congenital limb absence. Further research is needed to fully understand this relationship and its potential implications for the prevention and management of congenital limb absence.

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