1260 Medical Treatment Success of Recurrent Ectopic Pregnancy vs. Primary Ectopic Pregnancy: A Case Control Study

Abstract

Study Objective We aim in our study to evaluate whether there is a significant difference between women presenting with primary tubal ectopic pregnancy (EP) or recurrent ectopic pregnancy (REP) that are treated medically with methotrexate (MTX). Design A retrospective cohort study. Setting A tertiary medical center during 2010-2018. Patients or Participants All patients diagnosed with an EP and treated by intention of single-dose regimen of intramuscular MTX. Interventions Cases (REP) and controls (first-time only EP) were compared. Measurements and Main Results 262 patients had primary EPs and 32 had a REP. Women with REP had significantly higher gravidity order and higher incidence of previous abortions (5 vs. 3, median, p Conclusion Our study suggests that while women with REP may not represent a unique sub-group of women with EP, medical treatment success with a single-dose regimen of MTX is lower than expected and hence different regimens should be considered.