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Abstract
The skin consists of multiple tissue layers harboring distinct compartments of lipid metabolism. Because of limitations in separating and homogenizing skin tissue layers and given technological advances in mass spectrometry, there is a need for precise dissection of the microanatomy of skin combined with quantitative assessment of lipid distribution by employing state of the art technology. The aim of this project is to analyze lipid profiles by Liquid Chromatography - Mass Spectrometry (LC-MS) to detect lipid alterations in healthy skin.
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