Abstract
IntroductionMyocardial abnormalities have been identified in hypertrophic cardiomyopathy(HCM) gene mutation carriers without hypertrophy(G+LVH-). Some of these changes may be mutation-related but whether they can predict gene carriage in relatives of...
Highlights
Myocardial architectural abnormalities, have been identified in hypertrophic cardiomyopathy(HCM) gene mutation carriers without hypertrophy(G+LVH-)
Trabeculae ware charted by fractal analysis of high-resolution episcopic microscopy images using a box-counting method
We analyzed a single-center(UCL) G+LVH- case-control cohort to identify factors associated with gene carriage, evaluating anterior mitral valve leaflets(AMVL), wall thickness, clefts, trabeculae and other variables
Summary
“Advanced assessment of cardiac morphology and prediction of gene carriage by CMR in hypertrophic cardiomyopathy - the HCMNet/UCL collaboration.”. Journal of Cardiovascular Magnetic Resonance 16 (Suppl 1): O30. Captur et al Journal of Cardiovascular Magnetic Resonance 2014, 16(Suppl 1):O30 http://www.jcmr-online.com/content/16/S1/O30
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