Abstract

Rosacea is a common cutaneous condition characterized by erythema and vasodilation on the face. Facial flushing and telangiectasia are common symptoms of rosacea, which respond well to treatments with lasers with wavelengths that are selectively absorbed by oxyhemoglobin, such as the pulsed-dye laser (PDL), intense pulsed light (IPL), long-pulsed Nd:YAG and Alexandrite. Additionally, there have been increased data on microbiome diversity imbalance in rosacea patients. The current study was designed to investigate the efficacy and mechanism of long-pulsed Alexandrite laser (LPAL) in rosacea patients by analyzing the facial microbiome in patients receiving laser treatment.

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